It is well known that chemotherapy is less effective if the cancer is advanced the more advanced it is, the less effective shall the therapy be. But, the latest study shows the opposite effect of grape seed extract: if the cancer is more advanced, the extract would work better on the destruction.
Moreover, the study also shows that grape seed extract targets those cancer cells that have become highly resistant to chemotherapy, and it does not harm the healthy cells.
In the light of this extraordinary discovery, it is confirmed that grape seeds are more effective in the treatment of a late-stage cancer when compared to chemotherapy.
You will not only need less and less of the extract to kill the cancer cells, but the extract can also affect the cells that have become resistant to the medication, which makes the chemotherapy useless.
The research team conducted the experiment on colorectal cancer lines that represent every stage of the disease.
It usually takes more medications to kill cancer cells in the IV stage than in the II, but when it comes to grape seed extract it is just the opposite. Molly Derry, a doctoral candidate in the laboratory of the University of Colorado reveals:
It takes less than half of the concentration to control the cell growth and destroy 50% of the cells in the IV stage, compared to the amount that is required to achieve similar results in the second stage. Colon cancer cells may have more than 11,000 genetic mutations differences related to the DNA of the healthy cells. Traditional chemotherapy can target a specific mutation, and as the cancer grows the number of mutations increases. These changes may lead to resistance of the cancer to chemotherapy. On the other hand, many of the bioactive compounds in the grape seed extract can target more mutations. The efficacy of the extract grows as the number of mutations increases.
The study was conducted at the University of Colorado Cancer Center and it has been published in the journal Cancer Letters. The study involved cell cultures of colon carcinoma, not living beings, and that is exactly what modern medicine craves for.
The previous studies have documented that grape seeds can destroy cancer, and this study has found a possible way in which this could happen.
Scientists think that grape seed extract causes oxidative stress that leads to programmed cell death, also known as apoptosis.
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